A study of early predictors (Comorbidities and Etiology) of patient’s outcome after cirrhosis hospitalization

Group 19

Eva Frossard, Pauline Charpentier, Noy Tabul, Fabian Ziegler

Introduction

Objective: Understand patterns and correlations between early predictors Comorbidities and Etiologies, their numerical estimate CPS and Charlson index and cirrhosis’ patients outcome

Cirrhosis = condition in which the liver is scarred and permanently damaged.

Relevancy of the study: Cirrhosis is a leading cause of mortality in the world (11th), and finding accurate descriptive index is a useful tool to investigate the possible outcome of patients.

Materials - Dataset

Data set used: Early predictors of outcomes of hospitalization for cirrhosis and assessment of the impact of race and ethnicity at safety-net hospitals

733 patients
From 4 safety-net hospitals in the US
Male dominated study (67.31%)
Predominant age group [60; 70]
Main liver disease diagnosis
- Ascites (31%)
- Hepatic encephalopathy (21.2%)
- UGIB (19.9%)

Methods

Cleaning:

Extracting, renaming, reordering columns
Dropping non-available values them

Tidying:

Pivot_wider on Comorbidities
Pivot_wider on Etiologies

Augmenting:

Created categories for Mortality: no death, death in hospital, after 30 days, after 90 days
Creating age bins instead decade

Overview of comorbidities and etiologies

Etiology is the study of the factors that come together leading to a disease.
Comorbidity is an additional disease that can interact and coexist simultaneously with cirrhosis.